Don’t get your wires crossed
Analysis of results in a crossover clinical trial The analysis of a crossover clinical trial differs from that of a classical parallel trial. It must take into account the period and sequence effects.
Science without sense...double nonsense
Evidence Based Medicine pills
Science without sense...double nonsense
Evidence Based Medicine pills
Category Epidemiology
Strength through unity
Composite variable A composite variable combines variables to increase the number of events and decrease the sample size.
The ratio’s trap
Odds ratio vs risk ratio. Odds ratio and risk ratio are related concepts that can be interchanged when the prevalence of the effect is low, but not in other situations.
The chameleon
Adaptive clinical trial. In adaptive clinical trial, it is allowed to make changes in study design, as long as they are specified when planning the trial.
About pilots
Pilot studies. Pilot studies are carried out before the conventional trial in order to ensure the effect of the intervention and the feasibility of the study.