The King under review
Critical appraisal of treatment studies. Guidelines for critical appraisal of treatment studies are given, being the randomized clinical trial the most frequent design.
Science without sense...double nonsense
Evidence Based Medicine pills
Science without sense...double nonsense
Evidence Based Medicine pills
Tag Clinical trial
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Re-randomization in clinical trials. Re-randomization is the ability to randomize trial participants on more than one occasion, useful when large samples are required.
More than one rooster per pen
Factorial clinical trial. Factorial clinical trial allows testing more than one intervention with only one sample of participants. The clinical trial is the king of epidemiological designs. But it is also the most expensive to perform. And, in our times,…
Intention is what matters
Intention-to-treat analysis. Intention-to-treat analysis respects the initial group allocation of the participants when analyzing trial results.
The chameleon
Adaptive clinical trial. In adaptive clinical trial, it is allowed to make changes in study design, as long as they are specified when planning the trial.