Intention is what matters
Intention-to-treat analysis. Intention-to-treat analysis respects the initial group allocation of the participants when analyzing trial results.
Science without sense...double nonsense
Evidence Based Medicine pills
Science without sense...double nonsense
Evidence Based Medicine pills
Category Epidemiology
Don’t get your wires crossed
Analysis of results in a crossover clinical trial The analysis of a crossover clinical trial differs from that of a classical parallel trial. It must take into account the period and sequence effects.
Strength through unity
Composite variable A composite variable combines variables to increase the number of events and decrease the sample size.
The ratio’s trap
Odds ratio vs risk ratio. Odds ratio and risk ratio are related concepts that can be interchanged when the prevalence of the effect is low, but not in other situations.
The chameleon
Adaptive clinical trial. In adaptive clinical trial, it is allowed to make changes in study design, as long as they are specified when planning the trial.