de Student

The brewer

Student’s t distribution. Student’s t probability distribution allows estimating the value of the population mean of a random variable that follows a normal distribution when the parameter is extracted from a small sample and the population variance is unknown.

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ensayo clínico pragmático

Like life itself

Pragmatic clinical trial. We all know how difficult it is to make a new drug available to people who can benefit from it. From the moment a promising molecule is identified and somebody thinks that it may be useful, until…

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tamaño muestral

A strenuous effort, though unnecessary

Factors that condition the sample size. The need to perform a correct calculation of the sample size necessary for a study is reviewed, as well as the main factors that influence the sample required to demonstrate the effect considered relevant…

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NNT

The tribulations of maturity

Correct use of NNT. The NNT was designed to assess the beneficial effect of a treatment to reduce the risk of an unpleasant event occurring in an intervention group of interest, always with respect to what was observed in a…

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