Category Epidemiology

number remaining at risk

And what about me?

Number remaining at risk Today we are going to do an act of social justice. At least from the point of view of analyzing the results of clinical trials. You will wonder what the post of today is about. Well,…
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sensitivity and especificity

The guard’s dilemma

Sensitivity and specificity The world of medicine is a world of uncertainty. We can never be sure of anything at 100%, however obvious it may seem a diagnosis, but we cannot beat right and left with ultramodern diagnostics techniques or…
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randomized clinical trial

King of Kings

Randomized clinical trial There is no doubt that when doing a research in biomedicine we can choose from a large number of possible designs, all with their advantages and disadvantages. But in such a diverse and populous court, among jugglers,…
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case and control studies

From the hen to the egg

Case and control studies Surely someone overflowing genius has asked you on any occasion, with a smug look, what came first, the hen or the egg? Well, the next time you meet with someone like this, you can answer with…
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cohort studies

One about Romans

Cohort studies What a fellows, those Romans!. They came, they saw and they conquered. With those legions, each one with ten cohorts, each cohort with almost five hundred Romans with their skirts and strappy sandals. The cohorts were groups of…
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Classification of epidemiological studies

Which family you belong?

Classification of epidemiological studies As we already know from previous posts, the evidence-based medicine systematics begins with a knowledge gap that moves us to ask a structured clinical question. Once we have elaborated the question, we will use its components…
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impact

Simplifying the impact

Other impact numbers In epidemiological studies it is common to find a set of measures of effect such as risks in exposed and non-exposed, relative risks and risk reductions. However, in order for the analysis of a study to be…
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nnt's confidence interval

The tribulations of an interval

NNT’s confidence interval The number needed to treat (NNT) is an impact measure that tells us in a simple way about the effectiveness of an intervention or its side effects. If the treatment tries to avoid unpleasant events, the NNT…
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re-randomization

Regular customers

Re-randomization in clinical trials We saw in a previous post that sample size is very important. The sample should be the right size, neither more nor less. If too large, we are wasting resources, something to keep in mind in…
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random error

The fairground shotgun

Random error and systematic error A few days ago I was with my cousin in our neighborhood parties and to entertain a while, we were firing a shot at one of the booths, to see if we could take the…
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