And what about me?
Number remaining at risk. The number needed to treat is the most widely used measure of clinical impact in the analysis of the results of a clinical trial. However, the prognosis of patients in whom the outcome under study does…
Science without sense...double nonsense
Evidence Based Medicine pills
Science without sense...double nonsense
Evidence Based Medicine pills
Category Epidemiology
A weakness
Calculation of NNT in meta-analysis. The calculation of NNT (number needed to treat) in meta-analysis is described using RR and OR, which are more robust against variability in baseline risk.
The guard’s dilemma
Sensitivity and specificity. The concepts of sensitivity and specificity, predictive values and likelihood ratios are described, as well as the use of ROC curves.
King of Kings
Randomized clinical trial. The components of parallel randomized clinical trial are described, as well as the most common design variants (crossover, sequential, community trials).
From the hen to the egg
Case and control studies. Case and control studies, their variations, their association measures, and their absolute and relative impact measures are described. Surely someone overflowing genius has asked you on any occasion, with a smug look, what came first, the…