Evidence Based Medicine pills
Evidence Based Medicine pills
Factors that condition the sample size. The need to perform a correct calculation of the sample size necessary for a study is reviewed, as well as the main factors that influence the sample required to demonstrate the effect considered relevant…
Statistical significance vs clinical relevance. We must always prioritize the effect size and its clinical relevance over its statistical significance, which depends on the sample size.
Clinical relevance. We describe how the clinical relevance of the results of a study should be assessed, without being limited only to their statistical significance.
Equivalence and non-inferiority. Equivalence clinical trials aim to show that the new treatment is equivalent to the current one.