Tag Basic concepts

randomized clinical trial

King of Kings

Randomized clinical trial There is no doubt that when doing a research in biomedicine we can choose from a large number of possible designs, all with their advantages and disadvantages. But in such a diverse and populous court, among jugglers,…
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re-randomization

Regular customers

Re-randomization in clinical trials We saw in a previous post that sample size is very important. The sample should be the right size, neither more nor less. If too large, we are wasting resources, something to keep in mind in…
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run in period

Steady… ready…

Run in period Don’t!. Not so fast. Before you rush out there you have to be sure that everything is well prepared. It is difficult to conceive that anyone gets to run a marathon without preparing beforehand, without sufficient physical…
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factorial clinical trial

More than one rooster per pen

Factorial clinical trial The clinical trial is the king of epidemiological designs. But it is also the most expensive to perform. And, in our times, this is an important inconvenience to launch a trial. Usually in each trial an intervention…
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